Genetic background is associated with distinct patterns of proarrhythmogenic remodeling leading to atrial fibrillation in pigs with ischemic heart failure.

Basic Res Cardiol · 2026 · PMC13186903 · PMID 41951797

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did not reach statistical significanceno p-value reported

In the right atrium, genes related to ECM remodeling ( FN and MMP2 ) and profibrotic signaling ( CCN2 , TGFB , and JNK1 ) showed a clear upward trend, although these changes did not reach statistical significance (Fig. 5 ).

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