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Soluble uric acid suppresses neutrophil-mediated host defense in sepsis.

Nat Commun · 2026 · PMC13187337 · PMID 42156746

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4 b, c) and lowered plasma IL-6 concentrations, although the latter did not reach statistical significance (Fig. 4d ), in hyperuricemic CKD mice with and without CLP compared to vehicle controls.

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