Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.

Although the reductions in AST levels were greater in the UDCA group than in the placebo group at both week 4 and week 8, the differences did not reach statistical significance ( Supplementary Table 5 ).

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While AST did not show statistically significant improvement, a decreasing trend was evident in the UDCA group over the study period.

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