Serum sCD25 predicts mortality and reflects IL-2-driven dysregulation of CD4⁺CD25⁺ T cells in severe fever with thrombocytopenia syndrome.

Trop Med Health · 2026 · PMC13188480 · PMID 42063192

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an increasing trendno p-value reported

did not reach statistical significanceno p-value reported

Comparison of cell-type composition revealed that the proportion of CD25 + cells within the CD4+ T cell compartment showed an increasing trend in non-survivors compared with survivors at both the sample and cell levels, although this difference did not reach statistical significance (Additional file 2: Figure S3).

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