High-resolution metagenomic characterization of gut microbiota composition and functional pathways in irritable bowel syndrome.

To evaluate within-group variability, we performed a betadispersion analysis, which indicated a trend toward greater dispersion in the IBS group compared to HCs (mean distance to centroid: IBS = 0.39; HC = 0.35), although this difference did not reach statistical significance (permutation test, p = 0.061; Fig. 4 d).

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