DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general population.

EBioMedicine · 2026 · PMC13191633 · PMID 42114417

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nominally significantno p-value reported

Further mediation analyses revealed nominally significant mediation of the associations between the DMRs chr11.7597983.7598302 and chr1.39620300.39620625 with RHCV through the gene expression of PPF1BP2 (25.7% mediation) and MACF1 (16.9% mediation) (bootstrap-based tests, p-values < 0.05, but FDR >0.05, Table S16 ).

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