Combined supplementation with isochlorogenic acid and quercetagetin ameliorates dexamethasone-induced intestinal injury via attenuation of oxidative stress and inflammation.

In the intestinal mucosa, the injury group showed a significant increase in MDA content ( p < 0.05; Figure 2 ) and a highly significant decrease in CAT activity ( p < 0.01), while GSH activity remained unchanged ( p > 0.05) compared with the control group.

also in 132,142 other papers

Relative to the control group, the serum IL-1β and IL-4 levels of broilers in the combination group were significantly increased ( p < 0.05), TNF-α showed an increasing trend without statistical significance ( p > 0.05), and IL-10 was significantly decreased ( p < 0.05). 3.3 Effects of isochlorogenic acid combination on intestinal tissue of broilers With respect to intestinal morphology, compared with the control group, villus length in the ileum and jejunum of broilers of the injury group was significantly reduced ( p < 0.05; Figure 5 ), while that in the duodenum was markedly reduced ( p < 0.01).

also in 63,971 other papers

In contrast, although the intestinal mucosal MDA content decreased and CAT activity increased, these changes did not reach statistical significance.

also in 111,027 other papers