VEGF, TNF-α, and PCT efficiency for traumatic brain injury prognosis evaluation in the first 72 h.

A highly significant ( p = 0.004) PCT concentration demonstrated it to be a clinically meaningful effect size and a reliable biomarker in discriminating the progression of TBI post 72 h, with an AUC of 0.834 at 72 h and 0.607 at 24 h from the admission time.

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A moderate negative correlation was observed between PCT and VEGF ( r = −0.413, p = 0.07); however, this did not reach statistical significance.

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