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Somatic mutational profiling identifies aggressive and indolent disease phenotypes in well-differentiated pancreatic neuroendocrine tumors.

Front Oncol · 2026 · PMC13193833 · PMID 42180048

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In patients with metastatic tumors, the presence of a mutation in ATRX or DAXX had the longest overall survival, although these differences did not reach statistical significance ( Figure 5H ).

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