Keratin 20 deficiency phenocopies human UAB and drives bladder fibrosis via a mechanotransduction-TGF-β axis.

iScience · 2026 · PMC13194166 · PMID 42181253

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As before, mutants showed increased type I collagen and total collagen, and SB-431542 treatment significantly reduced type I collagen levels to near-normal and showed a trend toward reducing total collagen ( Figures 5 B–5E).

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