Aging modulates amyloid clearance kinetics during anti-amyloid therapy: evidence from real-world serial amyloid PET.

MMSE scores improved significantly at 6 months ( p = 0.003, Cohen’s dz = 0.701) and showed a trend toward improvement at 12 months ( p = 0.014, Cohen’s dz = 0.605), although this did not meet the prespecified significance threshold ( p < 0.01) applied to account for multiple comparisons ( Table 1 ).

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