Barely Significant
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The CD4<sup>+</sup> T cell population partners with Tpex CD8<sup>+</sup> T cells to mediate antitumor immunity in the tumor microenvironment.

Nat Commun · 2026 · PMC13194716 · PMID 41904165

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did not reach statistical significanceno p-value reported
In the Th1 group, these populations showed an upward trend that did not reach statistical significance, whereas CTL (PD-1−GZMB+ CD8+) tended to increase.

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