Ferroptosis and Wnt/β-Catenin Signaling Triggered by Environmentally Relevant Nanoscale Polypropylene Plastics in Human Intestinal Models.

ACS Environ Au · 2026 · PMC13195470 · PMID 42180196

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Consistent with this design, exposure of HSIOs to NPPP-1 elicited a notable reduction of viability in a dose-dependent manner ( Figure B) similar to our observations using murine intestinal organoids, where NPPP-1 treatment showed a trend toward reduced viability (∼55%) at the highest concentration tested.

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