Additional highly significant loci included regions near PABPC4L , USP42 , LOC102724431 , and LPP and signals near MGAT4C , GRM5 , ARHGAP15 , ARHGEF3 , and PPP1R12B ( Fig 6 B; Table S2 ).
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Integrating Polygenic Risk and Ocular Phenotyping Reveals an Axial-Length-Dominant Mechanism in High and Extreme High Myopia.
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Notably, HM and EHM shared several loci showing significant or near-significant associations in both analyses, including regions near PLPP3 , PDE4D , and RBFOX1 .