Cancer type-specific variation in patterns of driver alterations across 50,000 tumors.

Cancer Cell · 2026 · PMC13198192 · PMID 41895280

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did not reach statistical significanceno p-value reported

We therefore rescued any associations involving cancer genes with pan-cancer alteration frequency of 10% or higher (these comprise TP53 , CDKN2A , TERT , KRAS and PIK3CA ) and which were also altered in 10% or more in a given cancer type but did not reach statistical significance in our analysis.

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