Barely Significant
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Bone regenerative efficacy of binder-jet fabricated hydroxyapatite granules with and without biomimetic octacalcium phosphate-coated modification in a rat critical-sized calvarial defect model.

Regen Biomater · 2026 · PMC13198882 · PMID 42186540

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showed a trendno p-value reported
By 12 weeks, the HA group showed a trend toward increased bone formation compared to the Empty control group, although this was not statistically significant.

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