Self-amplifying COVID-19 mRNA vaccination induces longitudinally enhanced antibody function in a Phase 3 trial.

NPJ Vaccines · 2026 · PMC13199437 · PMID 41912532

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showed a trendno p-value reported

FcγRIIA-binding antibodies showed a trend toward enrichment for ARCT-154 recipients at the day 29–91 interval, with a few Spikes showing statistical significance compared to BNT162B2 recipients, but not nearly to the same degree as FcγRIIIA (Supplementary Fig. 6 ).

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