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Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability.

Nat Commun · 2026 · PMC13199580 · PMID 41912510

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U-CLLs with wildtype TP53 and RPS15 mutations only trended to a shorter overall survival (OS) compared to cases with wild-type RPS15 ( p = 0.096) but did not reach statistical significance.

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