Genetically Predicted Use of Common Analgesics and Risk of Chronic Obstructive Pulmonary Disease: A Bidirectional Mendelian Randomization Study.

Int J Chron Obstruct Pulmon Dis · 2026 · PMC13199608 · PMID 42199875

Europe PMC DOI

hedged sentence

0.8450

closest p · 16.9× alpha

0.8450

boldest claim

The sentences

did not reach statistical significanceP = 0.845not close (p > 0.1)

The MR-Egger analysis also showed a similar direction of effect, though it did not reach statistical significance (OR: 0.69, 95% CI: 0.02–25.65, P = 0.845), likely due to the lower statistical power of this method.

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