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Loss of peroxisomal membrane proteins PEX13 and PEX14 disrupts fatty acid oxidation and drives lipid imbalance.

Biosci Rep · 2026 · PMC13199795 · PMID 41860470

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PPARG gene expression remained suppressed in si- PEX14 transfected cells following FFA treatment compared with the FFA-treated nonspecific control (about 32%; P = 0.19), although this difference did not reach statistical significance.

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