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Eucalyptol Ameliorates Neuroendocrine Stress-Aggravated Rheumatoid Arthritis Through Anti-inflammatory, Antioxidant, and Chondroprotective Mechanisms Associated with NF-κB and MAPK Signaling Pathways.

Cureus · 2026 · PMC13200764 · PMID 42199596

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Eucalyptol at the higher dose (200 mg/kg) demonstrated comparable or slightly greater preservation of joint tissue architecture than MTX alone; however, these differences did not reach statistical significance, indicating broadly similar histopathological efficacy between the two monotherapy groups.

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