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Causal effects of plasma protein-protein ratios on lung cancer subtypes: A proteome-wide Mendelian randomization and mediation analysis.

Medicine (Baltimore) · 2026 · PMC13200959 · PMID 42175454

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nominally significantno p-value reported
An intersection analysis identified protein–protein ratios with nominally significant, directionally consistent effects across both databases, yielding 5 for LC (after excluding 1 ratio due to reverse causation, as detailed below), 4 for LUAD, 5 for LUSC, and 4 for SCLC (Fig. 3 A–H).

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