While the Genotype × Striatal Region interaction effect only approached significance, exploratory post hoc comparisons showed a significant genotype difference specifically in the DL striatum, a qualitative effect consistent with the DL striatum’s predominant role in LID formation and expression ( Girasole et al., 2018 ).
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Dopamine 2 receptor ablation from cholinergic neurons attenuates L-DOPA induced dyskinesias.
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