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Diet in Inflammatory Bowel Diseases: Efficacy, Tolerability, and Microbiome Effects Toward Personalized Management.

Dig Dis Sci · 2026 · PMC13201316 · PMID 41313534

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An exclusion diet for UC, known as the Ulcerative Colitis Exclusion Diet (UCED), was evaluated in a RCT involving patients with active, medication-refractory UC, comparing UCED alone, fecal transplantation (FT), and FT combined with UCED; the diet alone achieved the highest rates of steroid-free clinical remission at 8 weeks (40%), endoscopic remission (27%), and was the only intervention to induce mucosal healing (20%), outperforming FT with or without dietary conditioning, although most differences did not reach statistical significance [ 65 ].

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