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Treg-derived IFN-γ supports the differentiation of Th1-Treg in tumor immunity and autoimmunity.

Front Immunol · 2026 · PMC13201394 · PMID 42206029

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In terms of the absolute numbers of Th1-Tregs, we observed a downward trend in tumors, although it did not reach statistical significance, while the numbers in the spleen were comparable between the two groups ( Supplementary Figure 5A ).

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