Aberrant p53 fuels macrophage immunoregulatory polarization and refractory clinical outcome in urothelial carcinoma.

J Immunother Cancer · 2026 · PMC13202007 · PMID 42161402

Europe PMC DOI

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0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

showed a trendp=0.090so close (0.05 < p ≤ 0.1)

In the ZSHS cohort, high TAMs infiltration showed a trend toward worse OS in p53 Abn patients ( figure 2A,B , p53 Abn : median OS: 40 vs 90 months, log-rank p=0.090), while no such association was observed in the p53 WT subgroup.

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