The prebiotic group showed a trend toward calcium retention. 204 In a 12-month RCT, postmenopausal women were supplemented with SBD111, a synbiotic medical food containing prebiotic dietary fibers and microbial strains isolated from fresh fruits and vegetables. 205 In the full cohort, supplementation did not significantly reduce bone loss.
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The gut-bone axis: microbial metabolism and nutritional interventions for bone health.
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