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Enriched Environment Suppresses Neuronal Ferroptosis Through SIRT1/AKT/GSK3β-Dependent Glycogen Metabolic Reprogramming After Cerebral Ischemia-Reperfusion.

Antioxidants (Basel) · 2026 · PMC13203480 · PMID 42193192

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At the total protein level, Nrf2 expression was slightly reduced in the MCAO group compared with the Sham group, but the difference did not reach statistical significance, and EE did not significantly alter total Nrf2 abundance ( p > 0.05, Figure 3 G).

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