Study on the Mechanism of Action of Baicalein in Inhibiting the Invasion of <i>Streptococcus agalactiae</i>.

The clustering heatmap revealed that the metabolic changes in the baicalein-treated group were highly significant.

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The results showed that the expression of pbsP , an invasion-associated virulence gene, was significantly reduced, while the expression of hylB and cfb showed downward trends that did not reach statistical significance.

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Under baicalein treatment, there were no significant changes in hylB, fbsB , and cfb , although the mRNA expression of hylB and cfb showed a decreasing trend without statistical significance ( Figure 5 a–c).

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