Analysis of the Frequency and Associated Factors of Skin Toxicity in Patients Receiving Ribociclib-Based Therapy for Metastatic Breast Cancer.

However, this difference did not reach statistical significance (HR 0.71, 95% CI 0.36–1.41; log-rank p = 0.33), suggesting a trend toward improved PFS in patients experiencing cAEs, although the current sample size may have been insufficient to detect a statistically significant difference ( Figure 2 ).

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In the present study, although the development of cAEs did not demonstrate a statistically significant impact on PFS, a numerical trend toward superior PFS was observed in patients who experienced cAEs compared with those who did not.

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