Precision-Oriented Reconstruction After Spinal Sarcoma Resection: Integrating Surgical Strategy, Biologic Risk, and Emerging Technologies.

Notably, a recent pooled analysis of primary spinal sarcomas found that en bloc excision significantly improved overall survival in chondrosarcoma and Ewing sarcoma but did not reach statistical significance for spinal osteosarcoma, suggesting that the survival benefit of aggressive resection may be histotype-dependent and that systemic disease control remains the dominant prognostic factor in spinal osteosarcoma [ 45 ].

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