Potential Economic and Clinical Implications of Multi-Dose Intravenous Acetaminophen After Robotic-Assisted Prostatectomy: A Secondary Descriptive Analysis of Publicly Available Phase IV Trial Data (NCT02369211).

Although postoperative opioid consumption numerically favored IV acetaminophen, the difference did not reach statistical significance and may have been influenced by limited statistical power and perioperative multimodal analgesic co-interventions. 3.4.

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Although this difference was modest, it indicates a numerical trend toward shorter PACU stay among patients treated with acetaminophen; however, the difference was not statistically significant and should not be interpreted as evidence of clinically meaningful improvement in postoperative recovery efficiency.

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