Consistent with this, our exploratory analysis of 30 COAD specimens showed a trend where CALB2 protein expression was more prevalent in stage III tissues and frequently overlapped with the proliferation marker Ki67, suggesting a potential link between CALB2 and tumor cell proliferation.
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CALB2 Expression Is Associated with Tumor Progression and Prognosis in Colorectal Adenocarcinoma.
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The statistical analysis of the protein-to-GAPDH ratios confirmed that these alterations were highly significant, demonstrating that CALB2 knockdown effectively suppresses the mesenchymal phenotype ( Figure 5 A–D).