Modulation of mRNA Expression of Biomarkers in the UPR-PERK Pathway by Ellagic Acid in Metabolic Dysfunction-Associated Fatty Liver Disease.

Int J Mol Sci · 2026 · PMC13206915 · PMID 42196469

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

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an increasing trendp > 0.05actually significant

Figure 6 c shows the data for eIF2α protein expression, indicating that the HCD groups exhibited an increasing trend compared to the SD group, whereas the HCD + EA group showed a decrease in expression compared to the HCD group ( p > 0.05).

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did not reach statistical significanceno p-value reported

Although these changes did not reach statistical significance in all parameters, they reflect a pattern consistent with metabolic dysregulation.

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