Protonation States of Proton-Sensing Glutamate Residues in Transporter Sialin.

Int J Mol Sci · 2026 · PMC13207226 · PMID 42196605

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hedged sentence

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closest p

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boldest claim

The sentences

probably not significantno p-value reported

Given the location of E171 deep in the protein center, the electrostatic changes in the local environment caused by the arrival of the ligand at the luminal entrance of the pore are probably not significant enough to really influence the p K a of E171.

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