Circulating DNA and Neutrophil-Derived Biomarkers in Neonatal Sepsis.

CRP and IL-6 showed highly significant differences at all three time points (all p < 0.001), with CRP peaking at day 3 and IL-6 showing the largest difference at day 1 ( Figure 1 ).

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In a previous study, we demonstrated that NET formation markers did not differentiate EOS from non-infected neonates in a similar cohort, although cfDNA showed a trend toward elevation [ 1 ].

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