Digital Health Strategies in Heart Failure: Effects of Telemedicine and Remote Monitoring on Clinical Outcomes-A Systematic Review and Meta-Analysis.

J Clin Med · 2026 · PMC13207727 · PMID 42194840

Europe PMC DOI

hedged sentence

0.1400

closest p · 2.8× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.14not close (p > 0.1)

A prespecified subgroup analysis revealed a significant mechanistic gradient (p for interaction = 0.008): haemodynamic-guided monitoring conferred the largest mortality reduction (RR 0.71), followed by structured RPM (RR 0.79), whereas non-invasive telemonitoring alone did not reach statistical significance (RR 0.93; p = 0.14).

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