Osteoinductive and Biocompatibility Assessment of a 3D-Printed Polymeric-Hydroxyapatite Composite Interference Screw.

Implants A at the same timepoint showed a trend toward enhanced NB formation with closer apposition to the implant surface (IS), reduced FT interposition, osteocytes well-embedded within lacunae, organized bone marrow spaces (BM), and homogeneous bone matrix infiltration; scattered blood sinusoids were visible within the newly formed bone, consistent with early vascular support of the osseointegration response ( Figure 6 A(d–f)), suggesting a possible contribution of the surface coating to early osseointegration.

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