Microglial-Derived IGF-1 Serves as a Regulator for Neuroimmune Homeostasis During Viral-Induced Demyelination.

CD163 + Regulatory Myeloid Cells Disperse from CD8 T Cells and Lose Arginase1 at the Interface Iba1 + CD163 + regulatory myeloid cells (15,979 cells; 84.2% CX3CR1 + ) showed a trend toward reduced spatial enrichment with CD8 T cells in MG- Igf1 KO tissue (CN median z = 18.0, MG- Igf1 KO median z = 13.7; p _adj = 0.240; Figure 8 A), consistent in direction across five of six MG- Igf1 KO mice.

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