Rapid, intense pericholedochal fibrosis after preoperative biliary drainage: A prospective histologic study in pancreatoduodenectomy specimens.

Ann Hepatobiliary Pancreat Surg · 2026 · PMC13212015 · PMID 42014141

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did not reach statistical significancep < 0.001actually significant

Although this difference did not reach statistical significance, it is directionally consistent with the markedly higher absolute collagen area in the PBD group (25,315,551 ± 21,865,238 μm 2 vs. 112,668 ± 77,844 μm 2 ; p < 0.001).

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