Comparison of Xpert MTB/RIF Assay and the Targeted Next-Generation Sequencing for the Diagnosis of Pleural Tuberculosis: A Prospective Comparative Diagnostic Accuracy Study.

Infect Drug Resist · 2026 · PMC13212029 · PMID 42212056

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0.1600

closest p · 3.2× alpha

0.1600

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did not reach statistical significancep = 0.16not close (p > 0.1)

However, in sputum samples, despite the substantial difference in absolute sensitivity observed in the overall cohort ( Table 2 ), the difference in the paired subset did not reach statistical significance ( p = 0.16), likely due to the limited sample size (n=17).

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