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Integrated metabolomics and gut microbiota analyses reveal the protective effects of matrine in ulcerative colitis.

Front Chem · 2026 · PMC13213417 · PMID 42211404

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A heatmap visualization confirmed that most of these metabolites were markedly elevated in the Model group compared to the Control group, while the Matrine group exhibited a clear trend toward normalization ( Figure 7G ), suggesting that matrine ameliorates UC-associated metabolic disturbances.

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