In another randomized placebo-controlled clinical trial, memantine delayed time to cognitive decline, but the study did not reach statistical significance for its primary endpoint in part due to significant attrition from disease progression and death [ 5 ].
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Protocol for Neuro-Oncology Anywhere: Deploying Mayo Clinic's remote cognitive assessment battery and wearable device monitoring platform while assessing the impact of metformin on cognition and quality of life in patients with history of cranial radiation.
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