Microglia depletion alleviates the disruptions in circadian rhythms and anxiety caused by bmal1 deficiency.

At day 10, the fitted peak activity time in PLX5622-treated Bmal1−/− mice shifted from 0.82 h after midnight, approximately 00:49, to 2.22 h after midnight, approximately 02:13, suggesting a trend toward phase recovery, although the phase difference from untreated Bmal1−/− mice did not reach statistical significance.

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