PGR-mediated transcriptome identifies SOX9 as a critical regulator of progesterone production in human ovulatory follicles.

iScience · 2026 · PMC13214315 · PMID 42211115

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0.0510

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showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

Further experiments using a small interfering RNA (siRNA)-mediated knockdown approach also showed a trend toward reduced SOX9 mRNA levels in PGR siRNA-treated hGLCs ( p = 0.051), consistent with PGR-dependent control of SOX9 transcription ( Figure S2 B).

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