Unsupervised Immune Profiling Identifies Distinct Post-Transplant T-Cell Clusters Associated with Kidney Allograft Function.

Med Sci (Basel) · 2026 · PMC13214605 · PMID 42201030

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.1850

boldest claim

The sentences

a numerical trendp = 0.052so close (0.05 < p ≤ 0.1)

A time-by-cluster interaction was observed for the CD8-skewed cluster (β = −0.020 mg/dL per month, p = 0.040), with a numerical trend that did not reach statistical significance for the innate-like cluster (β = −0.052, p = 0.052), Figure 5 .

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did not reach statistical significancep = 0.185not close (p > 0.1)

At 12 months post-transplantation, serum creatinine levels showed a numerical gradient across clusters, with higher values observed in the CD8-skewed, intermediate in the innate-like cluster, and lowest in the CD4-dominant cluster, although these differences did not reach statistical significance ( p = 0.185).

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