Aerobic Fitness and Health-Related Phenotypes: A Two-Stage Phenome-Wide Mendelian Randomization Study.

Among the valid results from the discovery phase that met all MR assumptions in the validation phase and only failed to reach statistical significance in this second step (Supplemental Table 6, Supplemental Digital Content 1, https://links.lww.com/MSS/D391 ), we observed patterns suggestive of lower coronary atherosclerosis risk, a more favorable lipid profile (hypercholesterolemia and triglyceride-related lipoprotein traits), lower coagulation f

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