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Polycationic dendrimers synergizes with gefitinib to overcome EGFR<sup>Ex19Del</sup>-driven resistance in non-small-cell lung cancer.

Discov Oncol · 2026 · PMC13216407 · PMID 41995791

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showed a trendno p-value reported
Both A549 and H292 showed a trend to decrease p-ERK/ERK ratio upon PURE G4 -OEI 48 exposure, while PC-9 cells presented a trend to increase the p-ERK/ERK ratio after treatment, suggesting that the MAPK pathway was activated by PURE G4 -OEI 48 .

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