Differentiating Alzheimer's disease and vascular dementia via combined OCT and OCT‑angiography analysis.

In patients with AD, RNFL thickness in the superior and temporal quadrants was comparable to that of healthy controls; the nasal quadrant appeared thicker and the inferior quadrant thinner than controls, but these differences did not reach statistical significance.

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While most metrics did not differ significantly among groups, parafoveal superficial capillary plexus VAD showed marginally significant modest reductions in the AD group, with the effect being more pronounced in the inferior parafoveal region (Table 4 ).

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