Association between circulating metabolites and endometriosis: a bidirectional two-sample Mendelian randomization study.

Nominally significant associations were observed for several other metabolites; lower ratios of 3-hydroxybutyrate and saturated fatty acids to total fatty acids and of total cholesterol to total lipids in very low-density lipoproteins were associated with a higher EM risk (OR, 0.863; P =0.015; OR, 0.865; P =0.030; OR, 0.855; P =1.51×10 −4 ).

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